CD4 anticorps (FITC)

N° du produit ABIN6657901

N° du produit (Fournisseur): 200-502-m70

L’anticorps Rat Monoclonal anti-CD4 a été validé pour FACS et FM. Il convient pour détecter CD4 dans des échantillons de Souris.

Aperçu rapide pour CD4 anticorps (FITC) (ABIN6657901)

Antigène: CD4

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Clone: GK1-5

Détail du produit anti-CD4 anticorps (FITC)

N° du produit (Fournisseur): 200-502-m70

Fournisseur: Rockland

Fonction: CD4 Fluorescein Antibody

Réactivité croisée (Details): Reactivity is observed against mouse CD4.

Purification: Fluorescein conjugated CD4 Monoclonal Antibody was Protein G Purified and is directed against mouse CD4.

Stérilité: Sterile filtered

Immunogène: Anti-CD4 Antibody (Monoclonal) was produced by repeated immunizations with Mouse CTL clone V4.

Isotype: IgG2b kappa

Labeling Ratio: 2-8

Information d'application

Indications d'application:

Flow_Cytometry_Dilution: 0.1-1 μg/10^6 cells

IF_Microscopy_Dilution: User Optimized

Other: Sufficient to run approximately 500 tests

Commentaires:

Suggested Applications: Sufficient to run approximately 500 tests
Anti-CD4 is tested in Flow Cytometry (Cell Surface) and useful for Immunofluorescence. Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Tris Cl, 0.15 M Sodium Chloride, pH 8.0

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Date de péremption: 6 months

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet:

Synonyms: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4 Antibody, L3T4, T4

Background: CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Gene Name: CD4

ID gène: 12504

NCBI Accession: NP_038516

UniProt: P06332

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events